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Ball-and-Chain Inactivation of Ion Channels Visualized by Cryo-Electron Microscopy

Ball-and-Chain Inactivation of Ion Channels Visualized by Cryo-Electron Microscopy

Ion channels, which allow potassium and sodium ions to flow in and out of cells, are crucial in neuronal ‘firing’ in the central nervous system and for brain and heart function. These channels use a “ball-and-chain” mechanism to help regulate their ion flow, according to a new study led by Weill Cornell Medicine scientists. The study, published March 18 in…