Publications

Receptor’s Structure Reveals How It Functions in Heart Disease

Receptor’s Structure Reveals How It Functions in Heart Disease

The full-length structure of the atrial natriuretic peptide receptor, pictured here, sheds light on how it functions in heart disease. Two copies of the receptor crossing the cell membrane (middle layer) are shown in red and blue. Credit: Huang Lab Weill Cornell Medicine researchers have determined the full-length structure of a blood pressure-regulating hormone receptor for the first time, uncovering…

A Fully Automated AI-Based System for Assessing IVF Embryo Quality

A Fully Automated AI-Based System for Assessing IVF Embryo Quality

AI-based tool can assist embryologists in determining both the embryo quality score and ploidy status, providing a comprehensive assessment of the embryo. Courtesy of Suraj Rajendran. A new artificial intelligence-based system can accurately assess the chromosomal status of in vitro-fertilized (IVF) embryos using only time-lapse video images of the embryos and maternal age, according to a study from investigators at Weill…

New Study Reveals Where Memory Fragments are Stored

An unforgettable time at a restaurant is not just about the food. The odors, the decor, the sound of the band playing, the conversations, and many other features may combine to form a distinctive memory of the night. Later, reviving any one of these impressions alone may be sufficient to bring back the entire experience. A new study now reveals…

Ball-and-Chain Inactivation of Ion Channels Visualized by Cryo-Electron Microscopy

Ball-and-Chain Inactivation of Ion Channels Visualized by Cryo-Electron Microscopy

Ion channels, which allow potassium and sodium ions to flow in and out of cells, are crucial in neuronal ‘firing’ in the central nervous system and for brain and heart function. These channels use a “ball-and-chain” mechanism to help regulate their ion flow, according to a new study led by Weill Cornell Medicine scientists. The study, published March 18 in…