Christopher Mason, Ph.D.
- Director, WorldQuant Initiative for Quantitative Prediction and WorldQuant Foundation Research Scholar
- Professor of Computational Genomics in Computational Biomedicine in the Institute for Computational Biomedicine
- Professor of Neuroscience in the Brain and Mind Institute (secondary appointment)
1305 York Avenue, Room Y-13.15
New York, NY 10021
Techniques
- Animal Models (e.g., zebrafish)
- Bioinformatics
- Cell Sorting
- High Performance Computing
- In situ hybridization
- Machine Learning, AI, Deep Learning
- Mathematical Modeling and Simulations
Research Areas
Research Summary:
We utilize computational and experimental methodologies to identify and characterize the essential genetic elements that guide the function of the human genome, with a particular emphasis on the elements that orchestrate the development of the human brain. Our lab creates detailed cell-specific molecular maps of genetic, epigenetic, transcriptional, and translational activity, creating a draft of the molecular recipe for the creation of the brain. We also develop methods to detect, catalog and functionally annotate variants in the genetic pathways that control developmental processes and how they are perturbed to create disease. We aim to understand of the functional elements of the human genome well enough to enable, eventually, the ability to repair, re-engineer, or fortify these genetic networks within human cells.
Recent Publications: