Schedule 2018
qBio I
Thursday, September 6th, 2018 – Thursday, December 13th, 2018
Tuesdays and Thursdays, 5:30 PM – 7:00 PM
Location: C200 Weill Auditorium (or as indicated; n.b.: first day meets in A950)
1300 York Avenue; 2nd Floor, Room C200 (unless otherwise noted)
Midterm Exam: Thursday, November 1st (5:30 pm – 7:30 pm) in Room C200
Course Directors:
 Jason Banfelder (jbanfelder@rockefeller.edu)
 Luce Skrabanek (las2017@med.cornell.edu)
Teaching Assistants (qbiotas2018@gmail.com):
Office hours and locations:
 Shana Bergman
Wednesdays, 12pm, E511  Scott Kulm
Fridays, 10am, Belfer 1422  Nakul Yadav
Mondays, 7pm, CRC 1st floor
This course will be fully graded: (Honors, High Pass, Low Pass, Fail)
Class Sessions and Lecture Notes

Quantifying a Sample Distribution part I (R code)
Thursday, September 6th, 2018
(note: class meets in A950)
summary statistics, quantiles, SD vs. SEM; introduction to swirl 
Quantifying a Sample Distribution part II (R code)
Tuesday, September 11th, 2018
summary statistics, SD vs. SEM, measurement variation vs. biological variation 
Probability Density Functions and the Normal Distribution part I (R code)
Thursday, September 13th, 2018
binomial, Poisson, and normal distributions, testing for normality (part I): an introduction to formal statistical tests 
Probability Density Functions and the Normal Distribution part II (R code)
Tuesday, September 18th, 2018
testing for normality (part II): qqplots vs. formal tests 
Lab #1: Practical R (Rmd code)
Thursday, September 20th, 2018
Common data structures (vectors); Markdown; strategizing JeopRdy 
JeopRdy heats
MondayFriday, September 2428, 2018
(Note: times and locations TBA) 
Confidence Intervals and Contingency Tables (R code)
Tuesday, October 2nd, 2018
ttests, working with proportional data, why CIs are more informative than pvalues, study types (retrospective, prospective, and cross sectional), working with rare events 
Final JeopRdy
Thursday, October 4th, 2018 
pValues and Formal Statistical Testing (R code)
Tuesday, October 9th, 2018
duality between pvalues and CIs, statistical vs. biological significance, choosing an appropriate α, type I and type II errors 
Lab #2: Practical R
Thursday, October 11th, 2018
common data structures continued (lists and dataframes); understanding Type I error rates 
Statistical Power and Experimental Design (R code)
Tuesday, October 16th, 2018
why you cannot just add a few N to your dataset when p > 0.05, appreciating the economics (in time and money) of experimental design, statistical vs. biological significance revisited, designing experiments around hardtoobtain samples 
Multiple Hypothesis Testing and Nonparametric Tests (R code)
Thursday, October 18th, 2018
from Bonferroni to False Discovery Rate, dealing with nonnormal data, ttests revisited 
Midterm Exam Review (led by TAs)
Tuesday, October 23rd, 2018 
Bayesian Methods (R code)
Thursday, October 25th, 2018
how to incorporate prior knowledge into statistical models 
Midterm Exam
Thursday, November 1st, 2018 
Lab #3: Practical R (R code)
Tuesday, November 6th, 2018
the role of simulation in statistics, nonparametric tests, exploring the optimal stopping problem 
Correlation vs. Linear Regression (R code)
Thursday, November 8th, 2018
introduction to modeling in R; why is not the whole story 
Code quality
Tuesday, November 13th, 2018 
Fitting Model Parameters to Data (R code)
Thursday, November 15th, 2018
nonlinear regression, a statistical view of curve fitting, confidence intervals revisited 
Thanksgiving Break: No class
Week of November 20th, 2018
Tuesday, November 27th, 2018 
Quantitative Comparison of Models and ANOVA part I (R code)
Thursday, November 29th, 2018
how to avoid overfitting, Ftest and AICs, Ftests as a means of parameter estimation 
Quantitative Comparison of Models and ANOVA part II (R code)  Problem Set 3
Tuesday, December 4th, 2018
how to avoid overfitting, Ftest and AICs, Ftests as a means of parameter estimation 
Principal Component Analysis (R code)
Thursday, December 6th, 2018
data transformation and data reduction methods 
Introduction to ggplot2
Tuesday, December 11th, 2018
publicationquality graphics withggplot