Schedule 2018
qBio I
Thursday, September 6th, 2018 – Thursday, December 13th, 2018
Tuesdays and Thursdays, 5:30 PM – 7:00 PM
Location: C-200 Weill Auditorium (or as indicated; n.b.: first day meets in A-950)
1300 York Avenue; 2nd Floor, Room C-200 (unless otherwise noted)
Midterm Exam: Thursday, November 1st (5:30 pm – 7:30 pm) in Room C-200
Course Directors:
- Jason Banfelder (jbanfelder@rockefeller.edu)
- Luce Skrabanek (las2017@med.cornell.edu)
Teaching Assistants (qbiotas2018@gmail.com):
Office hours and locations:
- Shana Bergman
Wednesdays, 12pm, E-511 - Scott Kulm
Fridays, 10am, Belfer 1422 - Nakul Yadav
Mondays, 7pm, CRC 1st floor
This course will be fully graded: (Honors, High Pass, Low Pass, Fail)
Class Sessions and Lecture Notes
-
Quantifying a Sample Distribution part I (R code)
Thursday, September 6th, 2018
(note: class meets in A-950)
summary statistics, quantiles, SD vs. SEM; introduction to swirl -
Quantifying a Sample Distribution part II (R code)
Tuesday, September 11th, 2018
summary statistics, SD vs. SEM, measurement variation vs. biological variation -
Probability Density Functions and the Normal Distribution part I (R code)
Thursday, September 13th, 2018
binomial, Poisson, and normal distributions, testing for normality (part I): an introduction to formal statistical tests -
Probability Density Functions and the Normal Distribution part II (R code)
Tuesday, September 18th, 2018
testing for normality (part II): qqplots vs. formal tests -
Lab #1: Practical R (Rmd code)
Thursday, September 20th, 2018
Common data structures (vectors); Markdown; strategizing Jeop-R-dy -
Jeop-R-dy heats
Monday-Friday, September 24-28, 2018
(Note: times and locations TBA) -
Confidence Intervals and Contingency Tables (R code)
Tuesday, October 2nd, 2018
t-tests, working with proportional data, why CIs are more informative than p-values, study types (retrospective, prospective, and cross sectional), working with rare events -
Final Jeop-R-dy
Thursday, October 4th, 2018 -
p-Values and Formal Statistical Testing (R code)
Tuesday, October 9th, 2018
duality between p-values and CIs, statistical vs. biological significance, choosing an appropriate α, type I and type II errors -
Lab #2: Practical R
Thursday, October 11th, 2018
common data structures continued (lists and dataframes); understanding Type I error rates -
Statistical Power and Experimental Design (R code)
Tuesday, October 16th, 2018
why you cannot just add a few N to your dataset when p > 0.05, appreciating the economics (in time and money) of experimental design, statistical vs. biological significance revisited, designing experiments around hard-to-obtain samples -
Multiple Hypothesis Testing and Non-parametric Tests (R code)
Thursday, October 18th, 2018
from Bonferroni to False Discovery Rate, dealing with non-normal data, t-tests re-visited -
Midterm Exam Review (led by TAs)
Tuesday, October 23rd, 2018 -
Bayesian Methods (R code)
Thursday, October 25th, 2018
how to incorporate prior knowledge into statistical models -
Midterm Exam
Thursday, November 1st, 2018 -
Lab #3: Practical R (R code)
Tuesday, November 6th, 2018
the role of simulation in statistics, non-parametric tests, exploring the optimal stopping problem -
Correlation vs. Linear Regression (R code)
Thursday, November 8th, 2018
introduction to modeling in R; why is not the whole story -
Code quality
Tuesday, November 13th, 2018 -
Fitting Model Parameters to Data (R code)
Thursday, November 15th, 2018
non-linear regression, a statistical view of curve fitting, confidence intervals revisited -
Thanksgiving Break: No class
Week of November 20th, 2018
Tuesday, November 27th, 2018 -
Quantitative Comparison of Models and ANOVA part I (R code)
Thursday, November 29th, 2018
how to avoid over-fitting, F-test and AICs, F-tests as a means of parameter estimation -
Quantitative Comparison of Models and ANOVA part II (R code) | Problem Set 3
Tuesday, December 4th, 2018
how to avoid over-fitting, F-test and AICs, F-tests as a means of parameter estimation -
Principal Component Analysis (R code)
Thursday, December 6th, 2018
data transformation and data reduction methods -
Introduction to ggplot2
Tuesday, December 11th, 2018
publication-quality graphics withggplot