Overview

From different, but complementary perspectives, and taking advantage of advanced specialized methods, the biomedical research disciplines of Physiology and Biophysics seek to discover, analyze and explain the functions of the human body’s building blocks: cells, tissues and organs. The availability of information from genomics, imaging, and proteomics, combined with the power of computational methods, has enabled entirely new approaches for making these discoveries and relating them to the most basic molecular mechanisms. Most importantly, these new approaches make it possible to integrate, in the research activities of the Program’s faculty, the findings from genetics, structural biology, and cell and molecular biology with principles and representations from physics and engineering. Together, they create a systems-level view of function in physiological components (e.g., from the cell to the heart, and from the neuron to the nervous system). This new integrative perspective, termed Integrative Systems Biology, complements and completes the study of structure and mechanisms of the body’s building blocks from their embryonic development to their mature function, in both healthy and diseased states. The Physiology, Biophysics and Systems Biology (PBSB) graduate program is designed to engage students in education through research in current and innovative aspects of these three synergistic components of modern biomedicine.

News

Sep 2008:
Ameer Thompson's paper 'Molecular mechanism of pH sensing in KcsA potassium channels' from Dr. Nimigean's laboratory, was published in PNAS [PubMed]

Aug 2008:
Ronit V. Oren's paper 'Acquired and Inherited Abnormalities in the Sinoatrial Node' has been selected as the best paper in the session 'Computational Pathophysiology of Cardiac Cells' at the 12th World Multi-Conference on Systemics, Cybernetics and Informatics (WMSCI 2008), held in Orlando, FL this year.

Jul 2008:
Daniel Han's paper describing work done on his thesis project has been selected as an Accelerated Publication and Hot Article in the July 2008 issue of the journal Biochemistry. [PubMed]

Mar 2008:
We are proud to announce that Armen Kherlopian, a current graduate student in the Physiology, Biophysics and Systems Biology graduate program, was awarded the Department of Energy Computational Science Graduate Fellowship.

Feb 2007:
In a national ranking of graduate programs, carried out by the Chronicle of Higher Education, Weill Cornell's PBSB program was ranked #3 in Physiology and #10 in Biophysics. [Article]