Coming soon: Mutation detection from RNA-seq data using SNPseeqer and INDELseeqer !
NEW: ChIPseeqer, a comprehensive framework for analysis of ChIP-seq data, is now available for download.
Goodarzi H*, Elemento O*, Tavazoie S. Revealing global regulatory perturbations across human cancers. 2009. Submitted to Molecular Cell. *Equal Contribution

Da Piedade I, Eric Tang MH, Elemento O. DISPARE: A DIScriminative PAttern REfinement algorithm for Position Weight Matrices. 2009. BMC Bioinformatics, in press.

Ci W, Polo JM, Cerchietti L, Shaknovich R, Wang L, Yang N, Ye K, Farinha P, Horsman DE, Gascoyne RD, Elemento O*, Melnick A*. 2009. The BCL6 transcriptional program features repression of multiple oncogenes in primary B-cells and is deregulated in DLBCL, 2009. Blood, 113(22):5536-5548  Full Text  * Joint Corresponding Authors

Lu X, Li J, Elemento O, Tavazoie S, Wieschaus E. 2009. Revealing nucleocytoplasmic ratio regulated zygotic transcription during Mid Blastula Transition using a genomic approach. 2009. Development 136(12):2101-10  Full Text 
Highlighted in Nature Reviews Genetics

Legesse-Miller A, Elemento O, Pfau S, Forman J, Tavazoie S, Coller H. let-7 overexpression leads to an increased fraction of cells in G2/M, direct down-regulation of Cdc34 and stabilization of Wee1 kinase in primary fibroblasts. 2009. Journal of Biological Chemistry (JBC)
Online early release  Full Text  .

Elemento O*, Slonim N* and Tavazoie S. 2007. A universal framework for regulatory element discovery across all genomes and data-types (FIRE), Molecular Cell 28(2).
 Full Text  Web site. *Equal Contribution
Rated as 'Must Read' (Factor 6.0) by Faculty of 1000 Biology.
Highlighted in Nature Reviews Genetics

Elemento O. 2007. Developing a systems-level understanding of gene expression (Meeting Report, CSHL Systems Biology 2007), Genome Biology, 8:304
 Full Text  (subscription required),  PDF  (local copy)

De Renzis S, Elemento O, Tavazoie S and Wieschaus E. 2007. Unmasking the activation of the zygotic genome using chromosomal deletions in the Drosophila embryo, PLoS Biology, 5(5): e117
 Full Text  Suppl Material.
Highlighted in Nature Reviews Genetics, Highlighted in Nature

Elemento O, Tavazoie S. 2007. Fastcompare: a non-alignment approach for genome-scale discovery of DNA and mRNA regulatory elements using network-level conservation, Methods Mol Biol, 395:349-66
 Full Text  Suppl Material

Slonim N*, Elemento O*, Tavazoie S. 2006. Genotype-phenotype association reveals intrinsic modularity in genetic networks. Molecular Systems Biology 2:2006.0005
 Full Text  Suppl Material
*Equal Contribution

Chan CS*, Elemento O*, Tavazoie S. 2005. Revealing post-transcriptional regulatory interactions through network-level conservation. PLOS Computational Biology 1(7): e69
 Full Text  Suppl Material
*Equal Contribution

Elemento O, Tavazoie S. 2005. Fast and systematic genome-wide discovery of conserved regulatory elements using a non-alignment based approach. Genome Biology, 6:R18
 Full Text  Suppl Material

Gascuel O, Bertrand D, Elemento O. 2005. Recontructing the duplication history of tandemly repeated sequences. Book chapter (novel results, peer-reviewed) in: Mathematics of Evolution and Phylogeny, Oxford University Press.

Elemento O, Gascuel O. 2005. An exact and polynomial distance-based algorithm to reconstruct single copy tandem duplication trees, Journal of Discrete Algorithms 3:362–374 (extended version of CPM03, re-peer-reviewed)
 Full Text 

Elemento O, Lefranc M-P. 2003. IMGT/PhyloGene : an online tool for comparative analysis of IG and TR genes. Developmental Comparative Immunology. 27(9):763-79

Elemento O, Gascuel O. An exact and polynomial distance-based algorithm to reconstruct single copy tandem duplication trees. Proceedings of the Fourteenth Annual Symposium on Combinatorial Pattern Matching (CPM 2003), volume 2676 of Lecture Notes in Computer Science. Springer Verlag, 2003.

Elemento O. 2003. Phylogenetic analyses of tandemly repeated gene families and application to immunoglobulin and T cell receptor genes in IMGT. PhD Thesis, University of Montpellier/CNRS  PDF  (in French).

Elemento O, Gascuel O. Lefranc M.P. 2002. Reconstructing the duplication history of tandemly repeated genes. Molecular Biology and Evolution 19 :278-288.  Full Text 

Elemento O, Gascuel O. 2002. A fast and accurate distance-based algorithm for reconstructing tandem duplication histories. Bioinformatics. 2002, 18, S2:S92-S99.  Full Text 

Elemento O. 1999. Using Principal Component Analysis to initialize and validate Kohonen maps (in French). Proceedings of  the Annual French Classification Society Conference (SFC'99), pp325-331.